Mathematical Biophysics/Mathematical  Molecular Biosciences 

 

(235)  Kelin Xia and Guo-Wei Wei, A review of geometric, topological and graph theory apparatuses for the modeling and analysis of biomolecular data (2016) arXiv:1612.01735.

(234) Qing Zhu, Yuzhe Du, Yoshiko Nomura, Rong Gao, Zixuan Cang, Guo-Wei Wei, Dalia Gordon, Michael Gurevitz, James Groome and Ke Dong, The voltage-sensing module of domain III in an insect sodium channel modulates the action of both α and β toxins, (2018).

(233) Duc D. Nguyen and Guo-Wei Wei, Manifold learning of activity ligands and decoys (2018)

 

(232) Duc D Nguyen and Guo-Wei Wei, Multiscale weighted colored algebraic graphs (2018).

 

(231) Menglun Wang, Z.  X. Cang, R. Q. Guo, Heedeok Hong and Guo-Wei Wei, Prediction of membrane protein stability changes upon mutation, (2018).

 

(230) Zixuan Cang and Guo-Wei Wei, Persistent cohomology for datasets with heterogeneous information (2018). arXiv:1807.11120

 

(229) Zixuan Cang, Elizabeth Munch, and Guo-Wei Wei, Evolutionary homology on a dynamical system (2018). arXiv:1802.04677

 

(228) Duc D. Nguyen and Guo-Wei Wei, DG-GL: Differential geometry based geometric learning of molecular datasets (2018).  arXiv:1806.03765  

 

(227) Rundong Zhao, Menglun Wang, Yiying Tong and Guo-Wei Wei, A divide-and-conquer strategy for large-scale Eulerian solvent excluded surface, (2018)

 

(226) David Bramer and G. W. Wei, Blind prediction of protein B-factor and flexibility, Journal of Chemical Physics, (2018).

 

(225) Duc Duy Nguyen, Zixuan Cang, Kedi Wu, Menglun Wang, Yin Cao  and Guo-Wei Wei, Mathematical deep learning for pose and binding affinity prediction and ranking in D3R Grand Challenges, Journal of Computer Aided Molecular Design,  https://doi.org/10.1007/s10822-018-0146-6 (2018).

 

(224) Rundong Zhao, Zixuan Cang, Yiying Tong and Guo-Wei Wei, Protein Pocket Detection via Convex Hull Surface Evolution and Associated Reeb Graph, Bioinformatics, https://doi:10.1093/bioinformatics/bty598 (2018).

 

(223) Kedi Wu, Zhixiong Zhao, Renxiao Wang  and Guo-Wei Wei, TopP–S: Persistent Homology-Based Multi-Task Deep Neural Networks for Simultaneous Predictions of Partition Coefficient and Aqueous Solubility,  Journal of Computational Chemistry,  39, 1444-1454  (2018).  

 

(222) Kedi Wu and Guo-Wei Wei, Quantitative toxicity prediction using topology based multi-task deep neural networks,  Journal of Chemical Information and Modeling,   58, 520-531 (2018).  

 

(221) David Bramer  and G. W. Wei,  Multiscale weighted colored graphs for protein flexibility and rigidity analysis, Journal of Chemical Physics,  148, 054103  (2018). (This  work  was  featured  in  AIP Scilight)

 

(219) Z. X. Cang, Lin Mu and Guo-Wei Wei, Representability of algebraic topology for biomolecules in machine learning based scoring and virtual screening, PLOS Computational Biology,  14(1), e100592 (2018).

 

(218) Yuri A. Nedialkov, Kristopher Opron, Hailey L. Caudill1, Fadi Assaf, Amanda J. Anderson, Robert I. Cukier, Guo-Wei Wei and Zachary F. Burton,  Hinge action versus grip in translocation by RNA polymerase, Transcription, 9,1-16 (2018)

 

(216) Bao Wang, Chengzhang Wang, Kedi Wu and Guo-Wei Wei, Breaking the polar-nonpolar division in solvation free energy prediction, Journal of Computational Chemistry, 39, 217–232 (2018).

 

(215) Z. X. Cang and Guo-Wei Wei, Integration of element specific persistent homology and machine learning for protein-ligand binding affinity prediction, International Journal for Numerical Methods in Biomedical Engineering, 34 (2), e2914  (2018).

 

(214)  Guo-Wei Wei, Mathematics at the eve of a historic transition in biology, Molecular Based Mathematical Biology, 5, 138-141 (2017).

 

(213) Guo-Wei Wei, Persistent homology analysis of biomolecular data, SIAM News, 50 (10) December (2017).

 

(212) Z. X. Cang and Guo-Wei Wei, TopologyNet: Topology based deep convolutional and multi-task neural networks for biomolecular property predictions

, PLOS Computational Biology, 13(7), e1005690 (2017).

 

(211) Z. X. Cang and Guo-Wei Wei, Element specific persistent homology for the analysis and prediction of protein folding stability upon mutation, Bioinformatics,   33, 3549-3557 (2017).

 

(210) Duc D Nguyen, Tian Xiao, Menglun Wang  and Guo-Wei Wei, Rigidity strengthening: A  mechanism for protein-ligand binding,  Journal of Chemical Information and Modeling, 57, 1715-1721 (2017).

 

(209) Bao Wang, Zhixiong Zhao, Duc Nguyen and Guo-Wei Wei, Feature functional theory - binding predictor (FFT-BP) for the blind prediction of binding free energy, Theoretical Chemistry Account, 136, 55 (2017).

 

(207) Duc D Nguyen, Bao Wang and Guo-Wei Wei, Accurate,  robust and  reliable  calculations of Poisson-Boltzmann binding energies,  Journal of Computational Chemistry, 38,  941-948 (2017).

 

(206) Duan Chen and Guo-Wei Wei, A Review of Mathematical Modeling, Simulation and Analysis of Membrane Channel Charge Transport, Reference Module in Life Sciences, https://doi.org/10.1016/B978-0-12-809633-8.12044-8 (2017).

 

(205) Yongcheng Zhou and Guo-Wei Wei, Variational Methods for Biomolecular Modeling, in Variational Methods in Molecular Modeling, Edited by Jianzhong Wu, Springer Science+Business Media Singapore, 181-221, (2017).

 

(204) Beibei Liu, Bao Wang, Rundong Zhao, Yiying Tong and Guo-Wei Wei, ESES:  software for Eulerian solvent excluded surface, Journal of Computational Chemistry, 38, 446-466 (2017).

 

(203) Lin Mu, Kelin Xia and Guo-Wei Wei, Geometric and electrostatic modeling using molecular rigidity functions, Journal of Computational and Applied Mathematics, 313, 18-37 (2017).

 

(202) Duc D Nguyen and Guo-Wei Wei, The impact of surface area, volume, curvature and Lennard-Jones potential to solvation modeling, Journal of Computational Chemistry,  38, 24–36 (2017).

(201) Guo-Wei Wei and  Nathan A. Baker, Differential geometry-based solvation and electrolyte transport models for biomolecular modeling: A review. In Many-Body Effects and Electrostatics in Biomolecules, edited by Qiang Cui, Markus Meuwly, and Pengyu Ren, Pan Stanford, 417-464, (2016).

 

(200) Guo-Wei Wei, Mathematical Molecular Bioscience and Biophysics, SIAM News,  49 (7), (2016).

 

(199) Bao Wang, Zhixiong Zhao and Guo-Wei Wei, Automatic parametrization of non-polar implicit solvent models for the blind prediction of solvation free energies, Journal of Chemical Physics, 145, 124110 (2016).

 

(198) Duc D Nguyen, Kelin Xia and Guo-Wei Wei,  Generalized flexibility-rigidity index, Journal of Chemical Physics, 144, 234106 (2016).

 

(197) Kristopher Opron, Kelin Xia, Zachary F.  Burton and Guo-Wei Wei, Flexibility-Rigidity Index  for Protein-Nucleic Acid Flexibility and Fluctuation Analysis, Journal of Computational Chemistry,  37, 1283–1295 (2016).

 

(196) Zachary F. Burton, Kristopher Opron, Guowei Wei and  James H. Geiger, A model for genesis of transcription systems,   Transcription,  7, 1-13 (2016).

 

(195) Bao Wang and   Guo-Wei Wei,    Object-oriented persistent homology,  Journal of Computational Physics, 305, 276-299 (2016).

 

(194) Zixuan Cang, Lin Mu, Kedi Wu, Kris Opron, Kelin Xia and Guo-Wei Wei, A topological approach to protein classification, Molecular based Mathematical Biology, 3, 140-162 (2015)   

 

(193) Kelin Xia, Kristopher Opron and Guo-Wei Wei, Multiscale Gaussian network model (mGNM) and multiscale anisotropic network model (mANM), Journal of Chemical Physics, 143, 204106   (2015).

 

(192) Bao Wang and   Guo-Wei Wei, Parameter optimization in differential geometry based solvation models, Journal of Chemical Physics,  143, 134119 (2015).

 

(191) Kelin  Xia, Zhixiong Zhao   and    Guo-Wei Wei,  Multiresolution persistent homology for excessively large biomolecular datasets, Journal of Chemical Physics, 143, 134103 (2015).

 

(190) Kristopher Opron, Kelin Xia, and Guo-Wei Wei, Communication: Capturing protein multiscale thermal fluctuations, Journal of Chemical Physics, 142,   211101 (2015).

 

(189) Jinkyoung Park, Kelin Xia and G.W. Wei,  Atomic scale design and three-dimensional simulations of nanofluidic systems, Microfluidics and Nanofluidics,  19, 665-692 (2015).

 

(188) Kelin  Xia   and    Guo-Wei Wei,  Multidimensional persistence in  biomolecular data,   Journal of Computational Chemistry, 36, 1502-1520 (2015).

 

(187) Kelin  Xia, Zhixiong Zhao  and   Guo-Wei Wei,  Multiresolution topological simplification, Journal of Computational Biology, 22, 9, 1-5 (2015).

 

(185) Kelin  Xia   and    Guo-Wei    Wei,  Persistent topology for cryo-EM data analysis,    International  Journal  for  Numerical    Methods  in    Biomedical    Engineering,  31, e02719 (2015).

 

(182) Kelin  Xia, X.  Feng,  Yiying  Tong  and    Guo-Wei    Wei,  Persistent homology for the quantitative prediction of fullerene stability, Journal of Computational Chemistry, 36, 408-422 (2015).

 

(178) Kelin  Xia   and    Guo-Wei    Wei,  Persistent homology  analysis of protein structure, flexibility and folding,    International  Journal  for  Numerical    Methods  in    Biomedical    Engineering,  30, 814-844 (2014).

 

(177) Kristopher Opron, Kelin Xia, and Guo-Wei Wei, Fast and anisotropic flexibility-rigidity index for protein flexibility and fluctuation analysis, Journal of Chemical Physics, 140(23), 234105, (2014).

 

(176) Kelin Xia and Guo-Wei Wei, Molecular nonlinear dynamics and protein thermal uncertainty quantification, Chaos, 24, 013103 (2014).

 

 (174)  Kelin  Xia,  Xin  Feng,  Zhan Chen, Yiying  Tong  and    Guo-Wei    Wei,  Multiscale  geometric modeling of macromolecules I:  Cartesian representation, Journal of Computational Physics, 257, 912-936 (2014).

 

(173)  Kelin Xia, and Guo-Wei Wei, A stochastic model for protein flexibility analysis, Physical Review E, 88, 062709 (2013).

 

(172) X.  Feng,  Kelin  Xia, Zhan Chen, Yiying  Tong  and    Guo-Wei    Wei, Multiscale  geometric modeling of macromolecules II: Lagrangian representation, Journal of Computational Chemistry,  34, 2100-2120  (2013).

 

(171) Kelin Xia, Kristopher Opron and Guo-Wei Wei, Multiscale multiphysics and multidomain models — Flexibility and rigidity, Journal of Chemical Physics,  139, 194109  (2013).

 

(169)  Michael Daily, Jaehun Chun, Alejandro Heredia-Langner, Guo-Wei Wei, and Nathan Baker,  Origin of parameter degeneracy and molecular shape relationships in geometric-flow calculations of solvation free energies. Journal of Chemical Physics, 139, 204108 (2013).

 

(168) Guo-Wei Wei, Multiscale multiphysics and multidomain models I: Basic theory, Journal of Theoretical and Computational Chemistry, 12(8), 1341006, (2013)

 

(167) Jinkyoung Park and G.W. Wei,  A molecular level  prototype for  mechanoelectrical  transducers in  mammalian   hair cells, Journal of Computational Neuroscience, 35, 231-241, (2013).

 

(166)  Dennis G. Thomas, Jaehun  Chun, Zhan Chen, Guo-Wei Wei, Nathan A. Baker,  Parameterization  of a geometric flow implicit solvation  model,  Journal of Computational  Chemistry, 24, 687-695  (2013)

 

(165)  Emil Alexov and Guo-Wei Wei, Preface: Special issue on modeling  electrostatics in molecular biology (MEMB), Commun. Comput. Phys., 13(1) 1-5, (2013).

 

(164) Duan  Chen  and  Guo-Wei  Wei,    Quantum    dynamics    in    continuum    models  for  proton    transport  I:  Basic  formulation,    Communication  in  Computational  Physics,  13,  285-324 (2013) 

 

(163)  Langhua    Hu,  Duan  Chen  and  Guo-Wei  Wei,    High-order  fractional  partial  differential equations for molecular surface  construction, Molecular  Based  Mathematical Biology,  1-25  (2012).

 

(162) X.  Feng,  Kelin  Xia,  Yiying  Tong  and    Guo-Wei    Wei,  Geometric  modeling  of  organelles,  subcellular  structures   and  multiprotein  complexes,  International  Journal  for  Numerical    Methods  in    Biomedical    Engineering, 28, 1198-1223 (2012).

 

(161)  Zhan  Chen,    Shan    Zhao,  Jaehun  Chun, Dennis G. Thomas, Nathan    Baker,  Peter    Bates  and  Guo-Wei    Wei,  Variational  approach    for    nonpolar    solvation    analysis, Journal of Chemical Physics,  137, 084101 (2012).

(160) Anita T.  Layton  and  Guo-Wei Wei,   Editorials:  Interface  methods  for  biological  and  biomedical  problems,  International  Journal  for  Numerical    Methods  in    Biomedical    Engineering, 28, 289–290, (2012)

(159)  Duan  Chen  and  Guo-Wei    Wei,    Quantum    dynamics    in    continuum    models    for    proton    transport  ---    Generalized  correlation, Journal of Chemical Physics,  136,  134109  (2012)

 

(158)  Guo-Wei    Wei,    Qiong  Zheng,    Zhan  Chen,  and Kelin  Xia, Variational    multiscale    models  for  charge  transport, SIAM Review. 54(4),  699-754  (2012)

 

(157)  Yang  Wang,    Guo-Wei    Wei    and    Siyang    Yang,    Selective    extraction  of  entangled  textures  via    adaptive  PDE  transform,    Int.      J.    Biomed      Imaging,    Volume 2012 (2012), Article ID 958142 (2012).

 

(156)  Langhua    Hu    and  Guo-Wei    Wei,    Nonlinear    Poisson    equation    for    inhomogeneous  media.    Biophysical Journal,  103, 758–766 (2012).

 

(155)  Duan  Chen,    Zhan    Chen    and  Guo-Wei    Wei,    Quantum    dynamics    in    continuum    models    for    proton    transport    II:    Variational    solvent-solute      interface,    International  Journal  for  Numerical    Methods  in  Biomedical  Engineering,   28, 25-51 (2012)

 

(154)  Qiong  Zheng,    Siyang    Yang  and  Guo-Wei    Wei,    Molecular    surface    generation    using    PDE  transform.    International  Journal  for  Numerical    Methods  in    Biomedical    Engineering,    28, 291-316      (2012)

 

(150)  Zhan    Chen    and  G.  W.    Wei,    Differential    geometry    based    salvation    model    III:    Quantum    formulation,    Journal  of    Chemical    Physics, 135, 194108 (2011).

 

(149)  Qiong  Zheng    and  Guo-Wei    Wei,    Poisson-Boltzmann-Nernst-Planck      model.    Journal  of    Chemical    Physics,  134  (19),  194101,    (2011)    (It    was    the  most  downloaded  in  JCP  in  May    2011)

 

(146)  Qiong  Zheng,    Duan    Chen  and  Guo-Wei    Wei,    Second-order    Poisson-Nernst-Planck    solver    for    ion    transport.  Journal  of    Computational    Physics,  230,  5239-5262  (2011)

 

  (145)  Zhan    Chen,    Nathan    Baker    and  G.  W.    Wei,    Differential    geometry    based    salvation    model    II:    Lagrangian    formulation  (62  pages),    Journal    of    Mathematical    Biology,      63,  1139–1200,    (2011).

 

(144)  Weihua  Geng    and  G.W.  Wei,    Multiscale      molecular    dynamics    via    the    matched    interface    and    boundary    (MIB)    method,      Journal  of    Computational    Physics,    230,  435-457      (2011). 

     

(143)  Duan  Chen,    Zhan    Chen,  Changjun    Chen,  Weihua    Geng  and  Guo-Wei    Wei,    MIBPB:  A  software  package  for    electrostatic    analysis,    Journal  of    Computational    Chemistry,    32,  756–770    (2011). 

 

(141)  Zhan    Chen,    Nathan    Baker    and  G.  W.    Wei,    Differential    geometry    based  solvation  model      I:    Eulerian    formulation,  Journal  of    Computational    Physics,  229,    8231-8258  (2010).

 

(140)  Duan  Chen  and  Guo-Wei    Wei,        Modeling    and    simulation    of    nano-electronic  devices    (44  pages),      Journal  of    Computational    Physics,    229,  4431-4460,    (2010).

 

(139)  Changjun  Chen,    Rishu  Saxena,  and  Guo-Wei  Wei,    Differential    geometry    based    multiscale    model    for    virus  capsid    dynamics,    Int.      J.    Biomed    Imaging,    Volume  2010,  Article  ID  308627,  9  pages  (2010).

 

(138)  Guo-Wei,  Wei,        Differential    geometry    based    multiscale      models,    Bulletin  of    Mathematical    Biology,  volume  72,  1562-1622,    (2010).

 

(136)  G.W.  Wei  and  G.  Wang,    Editoral:  Special  issue  on  recent  advances  in  computational  techniques  for  biomedical  imaging,    Commun.  Numer.  Methods  Engng,  25,  581-582  (2009)

 

(135)  P.  Bates,  Z.  Chen,  Y.H.  Sun,  G.W.  Wei  and  S.  Zhao,  Geometric  and  potential  driving    formation  and  evolution    of    biomolecular  surfaces,  J.  Math.  Biol.  59,  193-231  (2009) 

 

(133)  Duan  Chen,  G.W.  Wei,  X.  Cong  and  Ge  Wang,    Computational  methods  for  optical  molecular  imaging,  Commun.  Numer.  Methods  Engng,    25,  1137-1161(2008).

 

(130)  W.H.  Geng,  S.N.  Yu  and  G.W.  Wei,  Treatment  of  charge  singularities  in  implicit  solvent  models,    J.    Chem.  Phys.,  127,  114106  (20  pages)    (2007).  Also  available  at  the  Virtual  Journal  of  Biological  Physics  Research    October  1,  2007

 

(129)  P.  Bates,  G.W.  Wei  and  S.  Zhao,  Minimal    molecular    surfaces  and  their  applications,    J.    Comput.  Chem.,  .,  29,  380-391  (2008).   

 

(128)  S.  N.  Yu,  W.  H.  Geng  and  G.W.  Wei,  Treatment  of  geometric  singularities  in  implicit  solvent  models,  J.    Chem.  Phys.,    126,    244108  (13  pages)    (2007).  ).  Also  available  at    the    Virtual  Journal  of  Biological  Physics  Research    July  1,  2007

 

(127)  Y.C.  Zhou,  M.    Feig  and  G.W.  Wei,  Highly  accurate  biomolecular  electrostatics  in  continuum  dielectric  environments,    J.  Comput.  Chem.  29,  87-97  (2008). 

 

(124)  G.W.  Wei,  Editoral:  Recent  advances  in  mathematical  methods  for  the  analysis  of  biomedical  image,  International  Journal  of    Biomedical    Imaging,  vol.  2006,  70578,  1,  (2006).

 

(121)    Ge  Wang,  Haiou  Shen  Wenxiang  Cong,  Shan  Zhao  and  G.W.  Wei,  Temperature    modulated    bioluminescence    tomography,  Optics  Express,    14  (17)    7852-7871  (2006).

 

(MB2) P. W.  Bates, G.W. Wei and Shan  Zhao, The minimal molecular surface, arXiv:q-bio/0610038 [q-bio.BM] (2006).

 

(MB1) G. W. Wei, Yuhui  Sun, Yongcheng Zhou and Michael Feig,  Molecular multiresolution surfaces, arXiv:math-ph/0511001v1 1 Nov 2005.